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The value of the blood test in predicting treatment outcome in nuchal translucency measurement–a preliminary report.
In fetal medicine high-risk pregnancies are commonly managed by monitoring the development of the fetus, by ultrasound and vaginal examination during the first trimester. We report on a prospective study of all pregnant women carrying a fetus with a nuchal translucency measurement > or =2.5 mm, (n = 206) at the obstetric ultrasound department of St. Olav’s University Hospital in Trondheim, Norway during the period of June 30, 1992 to November 13, 1994. A maternal serum alpha-fetoprotein (MSAFP) level at 11 + 0 to 13 + 6 weeks (first test) was compared to the results of umbilical cord blood (UmbCB) testing after birth. The umbilical cord was sampled by cardiotomy immediately after the cord was clamped. The cut-off MSAFP level was identified by maximising the Youden index in a receiver operating characteristic (ROC) analysis and was set at 200 mg/l (10.7 ng/ml). Patients with a MSAFP value below 200 mg/l (n = 71) had a good prognosis (4 cases with trisomy 21; 2 cases with structural malformations). Among 106 patients with an MSAFP level > or = 200 mg/l there were 5 cases of trisomy 21 (4.7%). All but one of the trisomy 21 fetuses were detected from the first test and the remaining case was diagnosed later because of structural malformations at a second test. The sensitivity and specificity of the method were 89 and 49%, respectively. The fetal survival rate without aneuploidy was 80% and the case-fatality-rate (CFR) was 9.4%. In 11 cases the fetus died before a diagnosis could be established. The sensitivity of the method in predicting fetal survival was not optimal (sensitivity 61.5%; specificity 86.7%). Our results indicate that the prognostic value of the blood test is good when the fetus is managed according to a conservative policy, but is not optimal when the fetus is managed according to a surgical policy.An American couple who were living in a $1.5 million home in Thailand have been arrested after the house was allegedly discovered to be a phony, according to multiple reports.
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Hp 2133 Drivers For Windows 7 32-bit Download’s first transfer request, and most are being obdurate. In the extreme case of Javier Pastore he might well have signed this summer – as would have been true of Filipe Luis if and when Chelsea had got around to the final stages. And, of course, Antonio Conte already knows how good he can be.
As does Mesut Ozil, whose view in the Premier League will have been informed by the Milan and Arsenal experience. He played a massive part in Arsenal becoming a force of a European identity, and went for it in the transfer window, even though it meant sacrificing the bulk of the market window. He was rewarded with one of the greatest final months in the Gunners’ history, winning a quadruple. Indeed the most infuriating thing about the failure to sign Pastore may be that Mesut Ozil may become one of the few defenders to exceed expectations in this English season.
7. Champion – Championship
Facebook Twitter Pinterest Championship play-offs: Aston Villa v Fulham. Photograph: Dan Mullan/Getty Images
Ashley Young to play a major role
If this side was a team of a year ago, Aston Villa would probably be top of the league. They are up there now because of the astonishing talent of Christian Benteke, the improvement of Mohamed Elneny, the solidity of Jordan Ayew, and because they are seemingly not short of goals.
As things stand, there are no guarantees in the Premier League, but nevertheless Aston Villa can expect to give the Premier League a good shake. Their style is fairly basic: everything is done in two passes, and there is little space. But to play to their strengths they need a defensive organisation that is built on discipline and organisation. And they have an excellent centre-half pairing in Ciar
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